G Protein-Coupled Receptor Peptide Ligand Library

Produktnummer ABIN2877721

Kurzübersicht für G Protein-Coupled Receptor Peptide Ligand Library (ABIN2877721)

Applikation: Binding Studies (Bind), Screening Assay (ScA)

Produktdetails

Produktmerkmale: Full Name: G Protein-Coupled Receptor Peptide Ligand Library

Anwendungsinformationen

Kommentare:

Packaged in 96 well plates
1.5 nanomoles of peptide in 15 micrograms BSA.

This library is being continuously updated to include all new and current peptides including GnRH(1-5) (GPR101 and GPR173), SDF-1-alpha (CXCR4 receptor), Ela-32 and Ela-21 (APJ), SCNH2/Apelin-prepropeptide(42-57), TLQP-21 (C3a or C1q receptor), D-[Lys3]GHRP-6 (CCR5), Neuronostatin (GPR107), Pepcan-12 (CB1) Fractalkine peptides, cysteine-modified or C-terminally truncated INSLs and truncated GLP-1Peptide 34 (GPR54), Fertilization promoting peptide (TCP11), Head Activator Neuropeptide (GPR37), Obestatin( GPR39), Neuromedin S, Neuropeptide S, QRFP-43, PBAN, P518, NPB & NPW, INSL 3 & 7, Endokinin A/B, AF9, BK), receptors (FM-4/TGR-1, NPSR, GPR100, GPR135, GPR142, GPR103, GPR7 & 8, LGR7 & 8, CG6986, NPR-1, PBAN-R) and references.

It has been suggested that several different active conformations of the receptor may exist dependent on the properties of the agonist. Therefore, properly selection with modified peptide ligands for a biased signalling properties may allow the development of drugs that selectively modulate only the therapeutically relevant physiological functions, thereby decreasing the risk of side effects.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Store at 2 to 4°C before hydration and at -70°C after rehydration. Most peptides are stable for approximately 3-6 month after rehydration. Typically, any peptide containing Tryptophane, Cystein and Methionine can be easily oxidized and are therefore less stable.